Multimorbidity in people living with HIV and cancer in Mexico




José H. Hernández-Jerónimo, Departamento de Medicina Interna, Hospital General “Dr. Jesús Gómez Maza”, Tuxtla Gutiérrez, Chiapas, México
Nancy C. Martínez-Rivera, Departamente de Infectología, Instituto Nacional de Cancerología, Ciudad de México, Mexico
Carolina Pérez-Jiménez, Departamento de Infectología, Instituto Nacional de Cancerología, Ciudad de México. Mexico
Patricia Volkow-Fernández, Departamente de Infectología, Instituto Nacional de Cancerología, Ciudad de México. Mexico
Alexandra Martin-Onraet, Departamente de Infectología, Instituto Nacional de Cancerología, Ciudad de México, Mexico


Background: Non-communicable diseases occur earlier in people living with HIV (PLWH) than in general population. Objective: The goal of this study was to estimate the prevalence of comorbidities in PLWH and cancer. Material and methods: In this retrospective study, we included PLWH > 40 years with a history of cancer, coming to the National Cancer Institute, between 2010 and 2019. Data collected included cancer type, comorbidities, frequency of polypharmacy, Patients were evaluated for depression with the Beck Inventory Depression-II Scale. Results: Of 125 patients, 69 % had at least one comorbidity; 32 % had two or more. Common comorbidities were dyslipidemia (54 %), hypertension (19 %), obesity (14 %), and diabetes (12 %). In patients ≥ 50 years, 29 (62 %) had a densitometry and 9 (31 %) had osteoporosis; 56 depression questionnaires were applied: 30 % had mild to severe depression. Being ≥ 50 years was associated with multimorbidity (p = 0.017). Conclusions: We report PLWH and cancer with a high prevalence of multimorbidity and poor screening of bone disease and mental health. An integrated approach to the PLWH is needed to improve the detection and management of non-communicable diseases.



Keywords: Cancer. Non-communicable diseases. Multimorbidity. HIV.




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