Oscar Rosas-Carrasco, Centro de Evaluación Geriátrica, Departamento de Salud, Universidad Iberoamericana, Ciudad de México, México
Teresa Álvarez-Cisneros, Dirección de Investigación, Instituto Nacional de Geriatría; Departamento de Medicina Interna, Hospital Médica Sur; dad de México, Ciudad de México
Isabel Omaña-Guzmán, Unidad de Bienestar Infantil, Hospital General de México “Dr. Eduardo Liceaga”, Ciudad de México, México
Background: Restless legs syndrome (RLS) is a prevalent and underdiagnosed neurologic sensory-motor disorder characterized by the urge to move the legs. Although RLS has been associated with various clinical conditions, data on its prevalence and related factors in older Latino adults, particularly in Mexico, remain limited. This study aimed to estimate the prevalence of RLS and its association with clinical conditions in adults aged 50 and over. Materials and methods: This is a secondary cross-sectional analysis from the Fragility, Dynapenia and Sarcopenia in Mexico cohort study. Adults aged 50 and over with data on RLS diagnosis based on International RLS Study Group 2003 criteria and other clinical variables were included. To assess the association between RLS and clinical factors, adjusted logistic regression models were performed. Results: A total of 847 participants were included. The prevalence of RLS was 8.6%. RLS was positively associated with anxiety (odds ratio [OR]: 2.57, p = 0.009), overweight/obesity (OR: 2.18, p = 0.021), polypharmacy (OR: 1.93, p = 0.017), and poor quality of life (OR: 2.17, p = 0.010). Conclusion: This study provides evidence of a positive association between RLS and overweight/ obesity, anxiety, polypharmacy, and poor quality of life. These findings highlight the need for further investigation into the biological pathways that underlie these associations.
Keywords: Restless legs syndrome. Older adults. Anxiety. Polypharmacy. Obesity. Quality of life.