Miguel A. Gamboa y Gamboa, Departamento de Pediatría, Clínica de Mérida, Mérida, Yucatán, México
Cecilia C. Polanco-Cab, Departamento de Pediatría, Clínica de Mérida, Mérida, Yucatán, México
Fortino Solórzano-Santos, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, Secretaría de Salud, Ciudad de México, México
Background: Multisystem inflammatory syndrome in children (MIS-C) has not been described in southeastern Mexico. Objective: To report the clinical and epidemiological aspects of MIS-C in a private hospital in Mérida, Yucatán. Material and methods: Retrospective, descriptive, consecutive case series study in children under 18 years of age, treated from January 2021 to March 2024. Patients diagnosed with MIS-C were selected. Patients underwent PCR testing, serological testing, or had known exposure to a family member with COVID-19. Descriptive statistics were analyzed with the χ2 test. Results: Seventy patients were included: 59 (84%) were hospitalized and 11 (16%) were followed up in the outpatient clinic, all with a diagnosis of MIS-C, median age 48 months (4-192), 44 (74.58%) were < 5 years old (p < 0.001) and predominance of males with 36 (61%). Of the hospitalized cases, 40 (67.79%) had the MIS-C phenotype and 19 (32.2%) had Kawasaki disease and MIS-C. MIS-C predominated in those aged ≤ 60 months. Gastrointestinal symptoms predominated in 68.5% of cases, and cardiovascular symptoms in 68.5%. There were 6 cases with coronary aneurysms (8.5%). Conclusions: Cases were most frequent in those aged < 5 years, with gastrointestinal and cardiovascular symptoms predominating. The presence of coronary aneurysms was low.
Keywords: Multisystem inflammatory syndrome in children. SARS-CoV-2. Coronary aneurysms. Kawasaki disease.