M.Fernanda Zarazúa-Jiménez, Unidad de Investigación Médica en Enfermedades Endocrinas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, México
M. Lourdes Basurto, Unidad de Investigación Médica en Enfermedades Endocrinas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, México
Cinthia G. Bonifaz-Bravo, Unidad de Investigación Médica en Enfermedades Endocrinas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, México
Edith Ruiz-Gastelum, Clínica de Hipertensión y Riesgo Cardiovascular, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado de Sonora (ISSSTESon), Hermosillo, Sonora, México
Mardia G. Lopez-Alarcón, Coordinación de Investigación en Salud, Centro Médico Nacional Siglo XXI, IMSS, Ciudad de México, México
Carlos A. Amores-Zúñiga, Unidad de Investigación Médica en Enfermedades Endocrinas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, México
Prediabetes is a condition that precedes diabetes with similar damage mechanisms but different diagnostic criteria. In prediabetes, there are certain promoting factors that encourage its development and once established, they favor the progression of comorbidity, especially cardiovascular. Excessive body weight is a main risk factor, usually part of prediabetes so it is recommended to implement lifestyle changes to prevent the development of diabetes, or even get to revert to normoglycemia. This may be possible if there is an adequate identification of risk factors and screening to establish individualized modifications and avoid associated complications. Prediabetes should not be underestimated, since it is part of the diabetes spectrum, and in the long term it has repercussions on quality and life expectancy. This document proposes 10 basic guidelines to broaden the vision of this entity, identifying in which cases there is a probability of remission, related damage mechanisms, risk factors, macrovascular complications that it entails, start of screening, diagnostic criteria, recommendations for lifestyle changes, and pharmacological and non-pharmacological treatment options.
Keywords: Prediabetes. Dysglycemia. Cardiovascular disease. Impaired glucose tolerance.